Ependymoma refers to a heterogeneous group of cancers that can occur at any age and is one of the most common types of brain cancer in children. The genetic causes for its development are largely unknown and there are no targeted treatments to date. Scientists from the “Hopp Children’s Cancer Center at the NCT Heidelberg” (KiTZ), in collaboration with colleagues from the U.S.A. and Canada, have now developed a molecular approach that opens new treatment prospects. The Hopp Children’s Cancer Center at the NCT Heidelberg (KiTZ) is a joint initiative of Heidelberg University Hospital and the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ). Targeted therapies in cancer medicine are often based on tumor genome sequencing – a technique that makes it possible to identify targets for precision drugs. However, in some cancer types, these structures have not been found to date. This includes ependymoma, a group of brain tumors that are considered to be largely resistant against chemotherapy. Therefore, it would be crucial to find new options for treating them. Ependymoma can affect children as well as adults. In children, it is one of the most frequent types of brain cancer. In the quest for novel therapeutic approaches in the… Read full this story
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